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Extended culture of 2D gastruloids to model human mesoderm development

2024-03-25

Abstract excerpt

Micropatterned human pluripotent stem cells (hPSCs) treated with BMP4 (2D gastruloids) are among the most widely used stem cell models for human gastrulation. Due to its simplicity and reproducibility, this system is ideal for high throughput quantitative studies of tissue patterning and has led to many insights into the mechanisms of mammalian gastrulation. However, 2D gastruloids have only been studied up to 48h...

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Literature Corpus work
8aa08b27-8912-524e-98a6-bf3d7a2c2bf3
DOI
10.1101/2024.03.21.585753
Open publication

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Extended culture of 2D gastruloids to model human mesoderm developmentDOI 10.1101/2024.03.21.585753
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