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Article

Evolution of lung adenocarcinoma from preneoplasia to invasive adenocarcinoma.

Cancer medicine - 1 Mar 2023

Zhu Jianfei, Wang Wenchen, Xiong Yanlu, Xu Shuonan, Chen Jiankuan, Wen Miaomiao, Zhao Yabo, Lei Jie, Jiang Tao

Abstract excerpt

OBJECTIVE: Mutations in driver genes contribute to the development and progression of lung adenocarcinoma (LUAD). However, in the dynamic evolutionary process from adenocarcinoma in situ (AIS) to minimally invasive adenocarcinoma (MIA) and eventually to invasive adenocarcinoma (IAC), the role of driver genes is currently unclear. This study aimed to analyse the role of driver gene status in the progression of...

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PMID: 36325966
DOI: 10.1002/cam4.5393
PMCID: PMC10028051

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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