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Article

The nonsmokers' and smokers' pathways in lung adenocarcinoma: Histological progression and molecular bases.

Cancer science - 1 Sept 2021

Okudela Koji, Matsumura Mai, Arai Hiromasa, Woo Tetsukan

Abstract excerpt

There could be two carcinogenetic pathways for lung adenocarcinoma (LADC): the nonsmokers' pathway and the smokers' pathway. This review article describes the two pathways with special reference to potential relationships between histological subtypes, malignant grades, and driver mutations. The lung is composed of two different tissue units, the terminal respiratory unit (TRU) and the central airway compartment...

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Source

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Identifiers

PMID: 34143937
DOI: 10.1111/cas.15031
PMCID: PMC8409399

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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