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Article

Effect of all-but-one conditional analysis for eQTL isolation in peripheral blood.

Genetics - 12 Jan 2023

Brown Margaret, Greenwood Emily, Zeng Biao, Powell Joseph E, Gibson Greg

Abstract excerpt

Expression quantitative trait locus detection has become increasingly important for understanding how noncoding variants contribute to disease susceptibility and complex traits. The major challenges in expression quantitative trait locus fine-mapping and causal variant discovery relate to the impact of linkage disequilibrium on signals due to one or multiple functional variants that lie within a credible set. We...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 36321965
DOI: 10.1093/genetics/iyac162
PMCID: PMC9836021

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