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Article

Influence of glutathione-related genetic variants on the oxidative stress profile of Mexican patients with psychotic disorders.

Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999) - 11 May 2023

Mayén-Lobo Yerye G, Alcaraz-Zubeldia Mireya, Dávila-Ortiz de Montellano David J, Motilla-Frías Blanca A, García-Manteca Mayumi Y, Ortega-Vázquez Alberto, Aviña-Cervantes Carlos L, Crail-Meléndez Edgar D, Ríos Camilo, López-López Marisol, Monroy-Jaramillo Nancy

Abstract excerpt

OBJECTIVE: The clinical trajectories of patients with psychotic disorders have divergent outcomes, which may result in part from glutathione (GSH)-related high-risk genotypes. We aimed to determine pharmacokinetics of clozapine, GSH levels, GSH peroxidase (GPx) activity, gene variants involved in the synthesis and metabolism of GSH, and their association with psychotic disorders in Mexican patients on clozapine...

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Identifiers

PMID: 36318479
DOI: 10.47626/1516-4446-2022-2783
PMCID: PMC10154007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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