Article

Polyunsaturated fatty acids (PUFA) Bimodality Unmasks xCT-Deficient Schizophrenia: Evidence of Two Distinct Biotypes

2025-07-22

Abstract excerpt

<p>Background and Hypothesis: Schizophrenia's heterogeneity hampers research, prevention, and treatment. We previously identified a bimodal distribution of red blood cell polyunsaturated fatty acids (PUFA) during acute schizophrenia, defining Low PUFA (LP) and High PUFA (HP) groups. We hypothesized that LP patients exhibit glutathione system dysfunction representing a distinct biotype characterized by redox dysreg...

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Literature Corpus work: 42d23c9e-96a9-5f75-85a1-ddb62dd55c20
DOI: 10.31234/osf.io/9bqte_v1

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Polyunsaturated fatty acids (PUFA) Bimodality Unmasks xCT-Deficient Schizophrenia: Evidence of Two Distinct BiotypesDOI 10.31234/osf.io/9bqte_v1Read

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