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Article

ABHD16A Negatively Regulates the Palmitoylation and Antiviral Function of IFITM Proteins

31 Oct 2022

Abstract excerpt

IFITM protein is the cells first line of antiviral defense that blocks early stages of viral replication; the underlying mechanism might be associated with the proper distribution in cells. The palmitoylation/depalmitoylation cycle can dynamically regulate protein localization, stability, and function. This work is the first one that found the critical enzyme that participates in the...

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PMID: 36314839
DOI: 10.1128/mbio.02289-22

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