Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Exocyst complex component 2 is a potential host factor for SARS-CoV-2 infection

22 Oct 2022

Abstract excerpt

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused an epidemic and spread rapidly all over the world. Because the analysis of host factors other than receptors and proteases has not been sufficiently performed, we attempted to identify and characterize host factors essential for SARS-CoV-2 infection using iPS cells and airway organoids (AO). Based on previous CRISPR screening and RNA-seq...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CRISPR and Genetic Engineering
Share to interferon and immune responses
Share to SARS-CoV-2 and COVID-19 Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 36310645
DOI: 10.1016/j.isci.2022.105427

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Exocyst complex component 2 is a potential host factor for SARS-CoV-2 infectionPMID 36310645Read ↗

Integrated multi-omics analyses identify key anti-viral host factors and pathways controlling SARS-CoV-2 infectionSemantic proximity Read ↗

SARS-CoV-2 Targets by the pscRNA Profiling of ACE2, TMPRSS2 and Furin ProteasesSemantic proximity Read ↗

DAZAP2 functions as a pan-coronavirus restriction factor by inhibiting viral entry and genomic replicationSemantic proximity Read ↗

Survival-based CRISPR genetic screens across a panel of permissive cell lines identify common and cell-specific SARS-CoV-2 host factorsSemantic proximity Read ↗

A multi-organoid platform identifies CIART as a key factor for SARS-CoV-2 infectionSemantic proximity Read ↗

Integrated multi-omics analyses identify anti-viral host factors and pathways controlling SARS-CoV-2 infectionSemantic proximity Read ↗

Low expression of EXOSC2 protects against clinical COVID-19 and impedes SARS-CoV-2 replicationSemantic proximity Read ↗

The scRNA-seq expression profiling of the receptor ACE2 and the cellular protease TMPRSS2 reveals human organs susceptible to COVID-19 infectionSemantic proximity Read ↗

Systematic genome-scale identification of host factors for SARS-CoV-2 infection across models yields a core single gene dependency; <i>ACE2</i>Semantic proximity Read ↗

Identification of Candidate COVID-19 Therapeutics using hPSC-derived Lung OrganoidsSemantic proximity Read ↗

SARS-CoV-2 Nsp15 endoribonuclease subverts host defenses to enhance viral fitness in lung cellsSemantic proximity Read ↗

Genome-wide bioinformatic analyses predict key host and viral factors in SARS-CoV-2 pathogenesisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.