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Genome-wide bioinformatic analyses predict key host and viral factors in SARS-CoV-2 pathogenesis

17 May 2021

Abstract excerpt

The novel betacoronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) caused a worldwide pandemic (COVID-19) after emerging in Wuhan, China. Here we analyzed public host and viral RNA sequencing data to better understand how SARS-CoV-2 interacts with human respiratory cells. We identified genes, isoforms and transposable element families that are specifically altered in SARS-CoV-2-infected...

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PMID: 34002013
DOI: 10.1038/s42003-021-02095-0

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