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Article

RAD51 and XRCC3 gene polymorphisms and the risk of developing acute myeloid leukemia.

Journal of investigative medicine : the official publication of the American Federation for Clinical Research - 1 Oct 2011

Hamdy Mona S, El-Haddad Alaa M, Bahaa El-Din Neveen M, Makhlouf Manal Mohamed, Abdel-Hamid Samah M

Abstract excerpt

RAD51 (Rec A homolog of E. coli) is a polymorphic gene and one of the central proteins in homologous recombination-DNA-double-stand breaks (HR-DNA-DSB) repair pathway, which is vital in maintaining genetic stability within a cell. The x-ray repair cross complementing (XRCC3) protein also functions in HR-DNA-DSB repair pathway and directly interacts with and stabilizes RAD51 and the closely related RAD51C. The aim...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 21725251
DOI: 10.2310/JIM.0b013e3182281da3

Genes

RAD51
XRCC3

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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