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Article

Significance of ATM Gene Polymorphisms in Chronic Myeloid Leukemia - a Case Control Study from India.

Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2016

Gorre Manjula, Mohandas Prajitha Edathara, Kagita Sailaja, Cingeetham Anuradha, Vuree Sugunakar, Jarjapu Sarika, Nanchari Santhoshirani, Meka Phanni Bhushann, Annamaneni Sandhya, Dunna Nageswara Rao, Digumarti Raghunadharao, Satti Vishnupriya

Abstract excerpt

BACKGROUND: Development of chronic myeloid leukemia (CML) involves formation of double strand breaks (DSBs) which are initially sensed by the ataxia telangiectasia mutated (ATM) signal kinase to induce a DNA damage response (DDR). Mutations or single nucleotide polymorphisms in ATM gene are known to influence the signaling capacity resulting in susceptibility to certain genetic diseases such as cancers. MATERIALS...

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Share to Ataxia Telangiectasia Mutated Proteins
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Share to Leukemia, Myelogenous, Chronic, BCR-ABL Positive

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Source

Identifiers

PMID: 26925685
DOI: 10.7314/apjcp.2016.17.2.815

Genes

ATM

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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