Article
Genetic polymorphisms and haplotypes of DNA repair genes in childhood acute lymphoblastic leukemia.
Pediatric blood & cancer - 1 Jan 2007
Pakakasama Samart, Sirirat Tanasan, Kanchanachumpol Saowanee, Udomsubpayakul Umaporn, Mahasirimongkol Surakameth, Kitpoka Pimpun, Thithapandha Amnuay, Hongeng Suradej
Abstract excerpt
BACKGROUND: Polymorphisms of DNA repair genes can alter protein structure and may impair DNA repair capacity. Defects in repairing damaged DNA lead to genetic instability and carcinogenesis. This study was performed to evaluate the effect of the polymorphisms of DNA repair genes on risk of childh...
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