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Article

The association between PD-1 gene polymorphisms and susceptibility to multiple sclerosis.

Immunological medicine - 1 Jun 2023

Hassani Nasrin, Salmaninejad Arash, Aslani Saeed, Kamali-Sarvestani Eskandar, Vessal Mahmood

Abstract excerpt

Programmed cell death 1 (PD-1) is an immune checkpoint and has been reported to be associated with several autoimmune diseases. We aimed to investigate the association between human PD-1 gene (PDCD1) polymorphisms and multiple sclerosis (MS). This case-control study was conducted on 229 MS patients and 246 healthy controls. Genotyping of rs36084323 (PD-1.1 G/A), rs11568821 (PD-1.3 G/A) and rs2227981 (PD-1.5 C/T)...

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Identifiers

PMID: 36308011
DOI: 10.1080/25785826.2022.2137967

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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