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Article

A Promoter Region Polymorphism in<i>PDCD-1</i>Gene Is Associated with Risk of Rheumatoid Arthritis in the Han Chinese Population of Southeastern China

1 Jan 2014

Abstract excerpt

Objective. Programmed cell death 1 (PD-1) induces negative signals to T cells during interaction with its ligands and is therefore a candidate gene in the development of autoimmune diseases such as rheumatoid arthritis (RA). Herein, we investigate the association of PDCD-1 polymorphisms with the risk of RA among Chinese patients and healthy controls. Methods. Using the PCR-direct sequencing analysis, 4 PDCD-1...

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PMID: 24804191
DOI: 10.1155/2014/247637

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