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The druggable genome: Twenty years later

30 Sept 2022

Abstract excerpt

The concept of the druggable genome has been with us for 20 years. During this time, researchers have developed several methods and resources to help assess a target's druggability. In parallel, evidence for target-disease associations has been collated at scale by Open Targets. More recently, the Protein Data Bank in Europe (PDBe) have built a knowledge base matching per-residue annotations with available...

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PMID: 36304325
DOI: 10.3389/fbinf.2022.958378

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