Article

Finding melanoma drugs through a probabilistic knowledge graph

2016-12-08

Abstract excerpt

Metastatic cutaneous melanoma is an aggressive skin cancer with some progression-slowing treatments but no known cure. The omics data explosion has created many possible drug candidates, however filtering criteria remain challenging, and systems biology approaches have become fragmented with many disconnected databases. Using drug, protein, and disease interactions, we built an evidence-weighted knowledge graph of...

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Literature Corpus work: 10dea7a2-ecea-5ec1-8b91-5cee0a88b37b
DOI: 10.7287/peerj.preprints.2007v2

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