Article
Druggability of human disease genes.
The international journal of biochemistry & cell biology - 1 Jan 2007
Sakharkar Meena Kishore, Sakharkar Kishore Ramaji, Pervaiz Shazib
Abstract excerpt
The availability of complete genome sequences and the wealth of large-scale biological datasets provide an unprecedented opportunity to elucidate the genetic basis of human diseases. Here we use integrative in silico approaches to provide an accurate description of gene functions to a set of 1737 highly curated disease genes in the human genome. This analysis is the first attempt on in silico identification of...
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