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Cellular Models of Alpha-Synuclein Aggregation: What Have We Learned and Implications for Future Study

20 Oct 2022

Abstract excerpt

Alpha-synuclein's role in diseases termed "synucleinopathies", including Parkinson's disease, has been well-documented. However, after over 25 years of research, we still do not fully understand the alpha-synuclein protein and its role in disease. In vitro cellular models are some of the most powerful tools that researchers have at their disposal to understand protein function. Advantages include good control...

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PMID: 36289910
DOI: 10.3390/biomedicines10102649

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