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Article

Modeling Parkinson's disease with induced pluripotent stem cells harboring α-synuclein mutations.

Brain pathology (Zurich, Switzerland) - 1 Jul 2017

Singh Dolt Karamjit, Hammachi Fella, Kunath Tilo

Abstract excerpt

Parkinson's disease (PD) is a common neurodegenerative condition affecting more than 8 million people worldwide. Although, the majority of PD cases are sporadic in nature, there are a growing number of monogenic mutations identified to cause PD in a highly penetrant manner. Many of these familial mutations give rise to a condition that is clinically and neuropathologically similar, if not identical, to sporadic...

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Identifiers

PMID: 28585381
DOI: 10.1111/bpa.12526
PMCID: PMC8029042

Genes

SNCA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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