Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Advances in understanding the function of alpha-synuclein: implications for Parkinson’s disease

15 May 2023

Abstract excerpt

The critical role of alpha-synuclein in Parkinson's disease represents a pivotal discovery. Some progress has been made over recent years in identifying disease-modifying therapies for Parkinson's disease that target alpha-synuclein. However, these treatments have not yet shown clear efficacy in slowing the progression of this disease. Several explanations exist for this issue. The pathogenesis of Parkinson's...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Neurological disorders and treatments
Share to Nuclear Receptors and Signaling
Share to Parkinson's Disease Mechanisms and Treatments

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 37183455
DOI: 10.1093/brain/awad150

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 19 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Advances in understanding the function of alpha-synuclein: implications for Parkinson’s diseasePMID 37183455Read ↗

The role of alpha-synuclein in Parkinson's disease: insights from animal models.Semantic proximity Read ↗

Structure, function and toxicity of alpha-synuclein: the Bermuda triangle in synucleinopathies.Semantic proximity Read ↗

Alpha-synuclein: its biological function and role in neurodegenerative diseases.Semantic proximity Read ↗

α-Synuclein in Parkinson's Disease: Pathogenic Function and Translation into Animal ModelsSemantic proximity Read ↗

Genetics of α-Synuclein: The Prime Pathological Player of Parkinson's Disease.Semantic proximity Read ↗

Alpha-Synuclein in Parkinson’s Disease: From Pathogenetic Dysfunction to Potential Clinical ApplicationSemantic proximity Read ↗

Molecular mechanisms of alpha-synuclein neurodegeneration.Semantic proximity Read ↗

Structure/function of α‐synuclein in health and disease: rational development of animal models for Parkinson's and related diseasesSemantic proximity Read ↗

Physiology and pathophysiology of alpha-synuclein. Cell culture and transgenic animal models based on a Parkinson's disease-associated protein.Semantic proximity Read ↗

In vitro models of synucleinopathies: informing on molecular mechanisms and protective strategiesSemantic proximity Read ↗

Alpha-Synuclein Aggregation in Parkinson's DiseaseSemantic proximity Read ↗

Parkinson's disease and alpha synuclein: is Parkinson's disease a prion-like disorder?Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.