Article

<i>In vivo</i> phenotyping of Parkinson-specific stem cells reveals increased a-Synuclein levels but no spreading

2017-05-19

Abstract excerpt

Parkinson′s disease is a progressive age-associated neurological disorder. One of the major neuropathological hallmarks of Parkinson’s disease is the appearance of protein aggregates, mainly consisting of the protein alpha-Synuclein. These aggregates have been described both in genetic as well as idiopathic forms of the disease. Currently, Parkinson’s disease patient-specific induced pluripotent stem cells (iPSCs)...

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Literature Corpus work: a9311a9f-cd80-5544-903c-50cab12ab479
DOI: 10.1101/140178

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