Genetic polymorphism in BIN1 rather than APOE is associated with poor recognition memory among men without dementia.

doi:10.1038/s41598-022-20587-9

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Article

Genetic polymorphism in BIN1 rather than APOE is associated with poor recognition memory among men without dementia.

Scientific reports - 24 Oct 2022

Mehta Kanika, Mohebbi Mohammadreza, Pasco Julie A, Williams Lana J, Walder Ken, Ng Boon Lung, Gupta Veer Bala

Abstract excerpt

Although several genetic polymorphisms have been linked with the risk of Alzheimer's disease, less is known about their impact on cognitive performance among cognitively healthy individuals. Our aim was to investigate the association of the genetic variant, rs744373 in the bridging integrator 1 gene (BIN1), the strongest genetic risk factor for Alzheimer's disease after the APOE ε4 allele, with different...

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PMID: 36280690
DOI: 10.1038/s41598-022-20587-9
PMCID: PMC9592585

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