Article
Potential contribution of the Alzheimer's disease risk locus BIN1 to episodic memory performance in cognitively normal Type 2 diabetes elderly.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology - 1 Apr 2016
Greenbaum Lior, Ravona-Springer Ramit, Lubitz Irit, Schmeidler James, Cooper Itzik, Sano Mary, Silverman Jeremy M, Heymann Anthony, Beeri Michal Schnaider
Abstract excerpt
In recent years, several promising susceptibility loci for late-onset Alzheimer's disease (AD) were discovered, by implementing genome-wide association studies (GWAS) approach. Recent GWAS meta-analysis has demonstrated the association of 19 loci (in addition to the APOE locus) with AD in the European ancestry population at genome-wide significance level. Since Type 2 Diabetes (T2D) is a substantial risk factor...
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