Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Potential genetic biomarkers in the early diagnosis of Alzheimer disease: APOE and BIN1.

Turkish journal of medical sciences - 1 Jan 2015

Kaya Gülhan, Gündüz Esra, Acar Muradiye, Hatipoğlu Ömer Faruk, Acar Burcu, Ilhan Atilla, Gündüz Mehmet

Abstract excerpt

BACKGROUND/AIM: Alzheimer disease (AD) is triggered by interactions of multiple genetic and environmental factors. The APOE gene E4 allele is the best-known risk factor for AD, yet it represents a small ratio of genetic factors. According to genome-wide association studies, the BIN1 gene is the second important risk factor for AD, following the APOE gene. We aimed to identify a novel biomarker indicating...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adaptor Proteins, Signal Transducing
Share to Alzheimer Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Apolipoproteins E

Share to Early Diagnosis

Share to Genetic Markers

Share to Nuclear Proteins

Share to Tumor Suppressor Proteins

Share to Turkey

Source

Identifiers

PMID: 26738348

Genes

APOE
BIN1
SDS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Potential genetic biomarkers in the early diagnosis of Alzheimer disease: APOE and BIN1.PMID 26738348Read ↗

BIN1 gene rs744373 polymorphism contributes to Alzheimer's disease in East Asian population.Semantic proximity Read ↗

Genetic evidence for the involvement of variants at APOE, BIN1, CR1, and PICALM loci in risk of late-onset Alzheimer's disease and evaluation for interactions with APOE genotypes.Semantic proximity Read ↗

Convergent lines of evidence support BIN1 as a risk gene of Alzheimer's disease.Semantic proximity Read ↗

The bridging integrator 1 Gene rs7561528 polymorphism contributes to Alzheimer's disease susceptibility in East Asian and Caucasian populations.Semantic proximity Read ↗

Genetic association of BIN1 and GAB2 in Alzheimer's disease: A meta-analysis and systematic review.Semantic proximity Read ↗

Association between apolipoprotein E gene polymorphisms and serum lipid indicators and Alzheimer's disease risk.Semantic proximity Read ↗

A polymorphism in the BIN1 gene influences its expression and is associated with the risk of Alzheimer's disease: An integrated analysis.Semantic proximity Read ↗

The Mechanistic Role of Bridging Integrator 1 (BIN1) in Alzheimer's Disease.Semantic proximity Read ↗

Increased expression of BIN1 mediates Alzheimer genetic risk by modulating tau pathology.Semantic proximity Read ↗

Association between methylation of BIN1 promoter in peripheral blood and preclinical Alzheimer’s diseaseSemantic proximity Read ↗

Bridging Integrator 1 (BIN1) Genotypes Mediate Alzheimer's Disease Risk by Altering Neuronal Degeneration.Semantic proximity Read ↗

Genetic variation in BIN1 gene and Alzheimer's disease risk in Han Chinese individuals.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.