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Identification of a novel target of SETD1A histone methyltransferase and the clinical significance in pancreatic cancer

22 Oct 2022

Abstract excerpt

Although histone H3K4 methyltransferase SETD1A is overexpressed in various cancer types, the molecular mechanism underlying its overexpression and its target genes in pancreatic ductal adenocarcinoma (PDAC) remain unclarified. We conducted immunohistochemical staining for SETD1A in 105 human PDAC specimens to assess the relationship between SETD1A overexpression and clinicopathological features. The function and...

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PMID: 36271761
DOI: 10.1111/cas.15615

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