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KDM1A and KDM3A promote tumor growth by upregulating cell cycle-associated genes in pancreatic cancer

25 Jun 2021

Abstract excerpt

Pancreatic cancer is a highly malignant cancer of the pancreas with a very poor prognosis. Methylation of histone lysine residues is essential for regulating cancer physiology and pathophysiology, mediated by a set of methyltransferases (KMTs) and demethylases (KDMs). This study surveyed the expression of methylation regulators functioning at lysine 9 of histone 3 (H3K9) in pancreatic lesions and explored the...

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PMID: 34171978
DOI: 10.1177/15353702211023473

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