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Article

Comparative analysis of the variability of the human leukocyte antigen peptide-binding pockets in patients with acute leukaemia.

British journal of haematology - 1 Jan 2023

Boukouaci Wahid, Rivera-Franco Monica M, Volt Fernanda, Wu Ching-Lien, Rafii Hanadi, Cappelli Barbara, Scigliuolo Graziana Maria, Kenzey Chantal, Ruggeri Annalisa, Rocha Vanderson, Gluckman Eliane, Tamouza Ryad

Abstract excerpt

The association between acute lymphoblastic leukaemia (ALL) and acute myeloid leukaemia (AML) and the human leukocyte antigens (HLA) has rarely been studied in terms of diversity of peptide-binding pockets. The objective of this study was to analyse whether motifs of HLA class I and class II peptide-binding pockets and/or their amino acid positions were differentially associated with ALL and AML. We included 849...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Histocompatibility Antigens Class I

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Share to Leukemia, Myeloid, Acute

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Source

Identifiers

PMID: 36263991
DOI: 10.1111/bjh.18517

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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