Article
Differential mitochondrial genome in patients with Rheumatoid Arthritis.
Autoimmunity - 1 Feb 2021
Jaiswal Kumar Sagar, Khanna Shweta, Ghosh Arup, Padhan Prasanta, Raghav Sunil Kumar, Gupta Bhawna
Abstract excerpt
BACKGROUND: Mitochondria play an important role in cell survival, function and lineage differentiation. Changes in mitochondrial DNA (mtDNA) may control mitochondrial functions and thus may impart an alternative cellular state thereby leading to a disease condition in the body. Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease wherein immune cells become self-reactive causing joint...
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