Article
Interleukin 16 polymorphism and susceptibility of rheumatoid arthritis disease in Egyptian population.
The Egyptian journal of immunology - 1 Oct 2021
Mostafa Shereen, Nasef Samah I, Hassan Amany M, Abdalla Azaa M, Omar Hanan H
Abstract excerpt
Rheumatoid arthritis (RA) is a systemic and multiple-stage disorder characterized by chronic inflammation with extensive synovitis. The genetic and environmental factors are associated with the risk for RA development. In RA, the induced IL-16 may play a role in initiating, sustaining and increasing the inflammatory response and development of synovitis, nevertheless IL-16's actual role in RA pathogenesis must be...
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