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Article

The SNPs of mitochondrial DNA displacement loop region and mitochondrial DNA copy number associated with risk of polymyositis and dermatomyositis.

Scientific reports - 7 Apr 2022

Zhao Yufei, Peng Chenxing, Lai Ruixue, Zhang Jingjing, Zhang Xiaoyun, Guo Zhanjun

Abstract excerpt

Oxidative damage-induced mitochondrial dysfunction may activate muscle catabolism and autophagy pathways to initiate muscle weakening in idiopathic inflammatory myopathies (IIMs). In this study, Single nucleotide polymorphisms (SNPs) in the mitochondrial displacement loop (D-loop) and mitochondrial DNA (mtDNA) copy number were assessed and their association with the risk of polymyositis and dermatomyositis...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Genetic Neurodegenerative Diseases

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Share to Polymorphism, Single Nucleotide

Source

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Identifiers

PMID: 35393495
DOI: 10.1038/s41598-022-09943-x
PMCID: PMC8990067

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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