Is there an Inflammation Role for MYD88 in Rheumatoid Arthritis?

doi:10.1007/s10753-020-01397-5

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Is there an Inflammation Role for MYD88 in Rheumatoid Arthritis?

Inflammation - 1 Jun 2021

Gomes da Silva Isaura Isabelle Fonseca, Lima Camilla Albertina Dantas, Silva José Eduardo Adelino, Rushansky Eliezer, Mariano Maria Helena Queiroz Araujo, Rolim Patrícia, Oliveira Renê Donizeti Ribeiro, Louzada-Júnior Paulo, Souto Fabricio Oliveira, Crovella Sergio, de Azevêdo Silva Jaqueline, Sandrin-Garcia Paula

Abstract excerpt

Rheumatoid arthritis (RA) is an autoimmune and inflammatory disease with strong genetic influence, especially upon immune response components. Several cytokines from the toll-like receptors activation pathway display recognized role for RA establishment. However, few studies have verified the role of key mediators such as MYD88 gene and its genetic variants. In the present study, we aim to evaluate the rs6853...

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PMID: 33405020
DOI: 10.1007/s10753-020-01397-5

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