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RH: a genetic metric for measuring intrahostPlasmodium falciparumrelatedness and distinguishing cotransmission from superinfection

1 Sept 2022

Abstract excerpt

Abstract Multiple-strain (polygenomic) infections are a ubiquitous feature of Plasmodium falciparum parasite population genetics. Under simple assumptions of superinfection, polygenomic infections are hypothesized to be the result of multiple infectious bites. As a result, polygenomic infections have been used as evidence of repeat exposure and used to derive genetic metrics associated with high transmission...

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PMID: 36246152
DOI: 10.1093/pnasnexus/pgac187

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