Article
Genetic relatedness analysis reveals the cotransmission of genetically related Plasmodium falciparum parasites in Thiès, Senegal.
Genome medicine - 24 Jan 2017
Wong Wesley, Griggs Allison D, Daniels Rachel F, Schaffner Stephen F, Ndiaye Daouda, Bei Amy K, Deme Awa B, MacInnis Bronwyn, Volkman Sarah K, Hartl Daniel L, Neafsey Daniel E, Wirth Dyann F
Abstract excerpt
BACKGROUND: As public health interventions drive parasite populations to elimination, genetic epidemiology models that incorporate population genomics can be powerful tools for evaluating the effectiveness of continued intervention. However, current genetic epidemiology models may not accurately simulate the population genetic profile of parasite populations, particularly with regard to polygenomic (multi-strain)...
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