Article
COIL: a methodology for evaluating malarial complexity of infection using likelihood from single nucleotide polymorphism data.
Malaria journal - 19 Jan 2015
Galinsky Kevin, Valim Clarissa, Salmier Arielle, de Thoisy Benoit, Musset Lise, Legrand Eric, Faust Aubrey, Baniecki Mary Lynn, Ndiaye Daouda, Daniels Rachel F, Hartl Daniel L, Sabeti Pardis C, Wirth Dyann F, Volkman Sarah K, Neafsey Daniel E
Abstract excerpt
BACKGROUND: Complex malaria infections are defined as those containing more than one genetically distinct lineage of Plasmodium parasite. Complexity of infection (COI) is a useful parameter to estimate from patient blood samples because it is associated with clinical outcome, epidemiology and dis...
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