Article
Within-household clustering of genetically related Plasmodium falciparum infections in a moderate transmission area of Uganda.
Malaria journal - 2 Feb 2021
Briggs Jessica, Kuchta Alison, Murphy Max, Tessema Sofonias, Arinaitwe Emmanuel, Rek John, Chen Anna, Nankabirwa Joaniter I, Drakeley Chris, Smith David, Bousema Teun, Kamya Moses, Rodriguez-Barraquer Isabel, Staedke Sarah, Dorsey Grant, Rosenthal Philip J, Greenhouse Bryan
Abstract excerpt
BACKGROUND: Evaluation of genetic relatedness of malaria parasites is a useful tool for understanding transmission patterns, but patterns are not easily detectable in areas with moderate to high malaria transmission. To evaluate the feasibility of detecting genetic relatedness in a moderate malaria transmission setting, relatedness of Plasmodium falciparum infections was measured in cohort participants from...
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