Article
A causal association of ANKRD37 with human hippocampal volume.
Molecular psychiatry - 1 Nov 2022
Xu Jiayuan, Xia Xianyou, Li Qiaojun, Dou Yan, Suo Xinjun, Sun Zuhao, Liu Nana, Han Yating, Sun Xiaodi, He Yukun, Qin Wen, Zhang Shijie, Banaschewski Tobias, Flor Herta, Grigis Antoine, Gowland Penny, Heinz Andreas, Brühl Rüdiger, Martinot Jean-Luc, Artiges Eric, Nees Frauke, Paus Tomáš, Poustka Luise, Hohmann Sarah, Walter Henrik, Sham Pak Chung, Schumann Gunter, Wu Xudong, Li Mulin Jun, Yu Chunshui
Abstract excerpt
Human hippocampal volume has been separately associated with single nucleotide polymorphisms (SNPs), DNA methylation and gene expression, but their causal relationships remain largely unknown. Here, we aimed at identifying the causal relationships of SNPs, DNA methylation, and gene expression that are associated with hippocampal volume by integrating cross-omics analyses with genome editing, overexpression and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.