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Article

Protective effect of tertiary lymphoid structures against hepatocellular carcinoma: New findings from a genetic perspective

14 Sept 2022

Abstract excerpt

Background: Tertiary lymphoid structures (TLS) have an effect on hepatocellular carcinoma (HCC), but the underlying mechanism remains to be elucidated. Methods: Intratumoral TLS (iTLS) was classified in the Cancer Genome Atlas-Liver Hepatocellular Carcinoma (TCGA-LIHC) cohort using pathological sections from the Cancer Digital Slide Archive. Univariate and multivariate Cox regression analyses were performed to...

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PMID: 36189217
DOI: 10.3389/fimmu.2022.1007426

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