Article

Intratumoral Tertiary Lymphoid Structures Promote Survival and Immunotherapy Response in Head Neck Squamous Cell Carcinoma

2022-08-26

Abstract excerpt

Tertiary lymphoid structures (TLSs) hold the potential role in the prediction of immunotherapy response in several clinical trials. TLSs in head neck squamous cell carcinoma (HNSCC) have been investigated through IHC analysis. Whereas there is no TLS gene signature to evaluate TLS neogenesis. We here proposed a TLS signature containing 13 chemokines and determined TLS-hi and TLS-low groups in HNSCC samples from Th...

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Literature Corpus work: 60eacc3b-587e-506b-841b-39aa0dfd1eaf
DOI: 10.21203/rs.3.rs-1987850/v1

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