Article
Admixture mapping of severe asthma exacerbations in Hispanic/Latino children and youth.
Thorax - 1 Mar 2023
Herrera-Luis Esther, Mak Angel C Y, Perez-Garcia Javier, Martin-Gonzalez Elena, Eng Celeste, Beckman Kenneth B, Huntsman Scott, Hu Donglei, González-Pérez Ruperto, Hernández-Pérez José M, Mederos-Luis Elena, Sio Yang Yie, Poza-Guedes Paloma, Sardón Olaia, Corcuera Paula, Sánchez-Machín Inmaculada, Korta-Murua Javier, Martínez-Rivera Carlos, Mullol Joaquim, Muñoz Xavier, Valero Antonio, Sastre Joaquin, Garcia-Aymerich Judith, Llop Sabrina, Torrent Maties, Casas Maribel, Rodríguez-Santana José R, Villar Jesús, Del Pozo Victoria, Lorenzo-Diaz Fabian, Williams L Keoki, Melén Erik, Chew Fook Tim, Borrell Luisa N, Burchard Esteban G, Pino-Yanes Maria
Abstract excerpt
BACKGROUND: In the USA, genetically admixed populations have the highest asthma prevalence and severe asthma exacerbations rates. This could be explained not only by environmental factors but also by genetic variants that exert ethnic-specific effects. However, no admixture mapping has been performed for severe asthma exacerbations. OBJECTIVE: We sought to identify genetic variants associated with severe asthma...
Topics
- Adolescent
- Humans
- Asthma
- Genome-Wide Association Study
- Hispanic or Latino
- Polymorphism, Single Nucleotide