Article
Genome-wide association study reveals a novel locus for asthma with severe exacerbations in diverse populations.
Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology - 1 Jan 2021
Herrera-Luis Esther, Espuela-Ortiz Antonio, Lorenzo-Diaz Fabian, Keys Kevin L, Mak Angel C Y, Eng Celeste, Huntsman Scott, Villar Jesús, Rodriguez-Santana Jose R, Burchard Esteban G, Pino-Yanes Maria
Abstract excerpt
BACKGROUND: Severe asthma exacerbations are a major cause of asthma morbidity and increased healthcare costs. Several studies have shown racial and ethnic differences in asthma exacerbation rates. We aimed to identify genetic variants associated with severe exacerbations in two high-risk populations for asthma. METHODS: A genome-wide association study of asthma in children and youth with severe exacerbations was...
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