Article
Admixture mapping of asthma in southwestern Europeans with North African ancestry influences.
American journal of physiology. Lung cellular and molecular physiology - 1 May 2020
Guillen-Guio Beatriz, Hernández-Beeftink Tamara, Marcelino-Rodríguez Itahisa, Rodríguez-Pérez Héctor, Lorenzo-Salazar Jose M, Espinilla-Peña Marta, Corrales Almudena, Pino-Yanes Maria, Callero Ariel, Perez-Rodriguez Eva, Villar Jesús, González-Montelongo Rafaela, Flores Carlos
Abstract excerpt
The prevalence of asthma symptoms in Canary Islanders, a southwestern European population from Spain, is almost three times higher than the country average. Because the genetic risks identified so far explain <5% of asthma heritability, here we aimed to discover new asthma loci by completing the first admixture mapping study in Canary Islanders leveraging their distinctive genetic makeup, where significant...
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