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Article

Clinical and NGS predictors of response to regorafenib in recurrent glioblastoma

28 Sept 2022

Abstract excerpt

Predictive factors for response to regorafenib in recurrent glioblastoma, IDH-wildtype, are scarcely recognized. The objective of this study was to identify molecular predictive factors for response to regorafenib using a clinically available platform. We analyzed a prospective cohort of 30 patients harboring recurrent glioblastoma, IDH-wildtype, and treated with regorafenib. Next-generation sequencing (NGS)...

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PMID: 36171338
DOI: 10.1038/s41598-022-20417-y

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