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Predictive biomarkers investigated in glioblastoma

5 Aug 2014

Abstract excerpt

Glioblastoma is the most aggressive primary brain tumor in adults. Consequently, new therapeutic strategies are needed. Tumor response to cytotoxic chemotherapy is heterogeneous across patients. Interestingly, predictive biomarkers of response to these classic chemotherapeutic agents have been identified in neuro-oncology (i.e., 1p/19q co-deletion, IDH mutation and O6-methylguanine DNA-methyltransferase promoter...

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PMID: 25096963
DOI: 10.1586/14737159.2014.945436

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