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NAD+, Sirtuins and PARPs: enhancing oocyte developmental competence

1 Jan 2022

Abstract excerpt

Oocyte quality is the limiting factor in female fertility. It is well known that maternal nutrition plays a role in reproductive function, and manipulating nutrition to improve fertility in livestock has been common practice in the past, particularly with respect to negative energy balance in cattle. A deficiency in nicotinamide adenine dinucleotide (NAD+) production has been associated with increased incidences...

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PMID: 36171094
DOI: 10.1262/jrd.2022-052

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