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Article

Sirtuin Functions in Female Fertility: Possible Role in Oxidative Stress and Aging

1 Jan 2015

Abstract excerpt

In search for strategies aimed at preventing oxidative threat to female fertility, a possible role of sirtuins has emerged. Sirtuins (silent information regulator 2 (Sir2) proteins), NAD(+) dependent enzymes with deacetylase and/or mono-ADP-ribosyltransferase activity, are emerging as key antiaging molecules and regulators in many diseases. Recently, a crucial role for SIRT1 and SIRT3, the main components of...

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PMID: 26075037
DOI: 10.1155/2015/659687

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