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Article

Nicotinamide Adenine Dinucleotide Deficiency and Its Impact on Mammalian Development.

Antioxidants & redox signaling - 1 Dec 2023

Dunwoodie Sally L, Bozon Kayleigh, Szot Justin O, Cuny Hartmut

Abstract excerpt

Significance: Nicotinamide adenine dinucleotide (NAD) is an important molecule synthesized from tryptophan or vitamin B3 and involved in numerous cellular reactions. NAD deficiency during pregnancy causes congenital NAD deficiency disorder (CNDD) characterized by multiple congenital malformations and/or miscarriage. Studies in genetically engineered mice replicating mutations found in human patient cases show...

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Identifiers

PMID: 37300479
DOI: 10.1089/ars.2023.0349

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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