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The NAD+ precursor nicotinamide riboside protects against postovulatory aging in vitro

26 Oct 2024

Abstract excerpt

Postovulatory aging (POA) of oocytes is clinically significant as it mirrors the degeneration observed in maternally aged oocytes, leading to substantial impairments in oocyte quality and the success rates of artificial reproductive technology (ART). The molecular alterations associated with POA, such as the degeneration of the first polar body, an increase in perivitelline space, reactive oxygen species (ROS)...

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PMID: 39460833
DOI: 10.1007/s10815-024-03263-x

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