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Article

Exploring the association of interleukin polymorphisms with aggression and internalizing behaviors in children and adolescents.

Brain and behavior - 1 Nov 2022

Pouget Jennie G, Bryushkova Lyubov, Koyama Emiko, Zai Clement C, Fonseka Trehani M, Mueller Daniel, Kennedy James L, Beitchman Joseph H

Abstract excerpt

BACKGROUND: There is growing evidence that inflammation influences mental health. Blood interleukin levels, which regulate inflammation, have been linked to aggression and internalizing behaviors. We performed a hypothesis-driven genetic study to (1) evaluate the association of IL1B, IL2, and IL6 gene variants with aggression and internalizing behaviors and (2) explore gene-environment interactions with childhood...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 36168941
DOI: 10.1002/brb3.2753
PMCID: PMC9660418

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