Article
Differential DNA methylation regions in cytokine and transcription factor genomic loci associate with childhood physical aggression.
PloS one - 1 Jan 2013
Provençal Nadine, Suderman Matthew J, Caramaschi Doretta, Wang Dongsha, Hallett Michael, Vitaro Frank, Tremblay Richard E, Szyf Moshe
Abstract excerpt
BACKGROUND: Animal and human studies suggest that inflammation is associated with behavioral disorders including aggression. We have recently shown that physical aggression of boys during childhood is strongly associated with reduced plasma levels of cytokines IL-1α, IL-4, IL-6, IL-8 and IL-10, later in early adulthood. This study tests the hypothesis that there is an association between differential DNA...
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