Article
Computational identification of gene-social environment interaction at the human IL6 locus.
Proceedings of the National Academy of Sciences of the United States of America - 23 Mar 2010
Cole Steven W, Arevalo Jesusa M G, Takahashi Rie, Sloan Erica K, Lutgendorf Susan K, Sood Anil K, Sheridan John F, Seeman Teresa E
Abstract excerpt
To identify genetic factors that interact with social environments to impact human health, we used a bioinformatic strategy that couples expression array-based detection of environmentally responsive transcription factors with in silico discovery of regulatory polymorphisms to predict genetic loc...
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